Antigen mutation is divided into antigenic drift and antigenic shift. Antigenic drift: refers to the small mutation of the antigen caused by the mutation of the genome, does not produce a new subtype, belongs to quantitative change, no qualitative change. Mostly cause small and medium epidemics of influenza. Antigen drift: Large-scale or complete mutation of influenza virus antigens.
Antigenic variation
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Antigen mutation is divided into antigenic drift and antigenic shift. Antigenic drift: refers to the small mutation of the antigen caused by the mutation of the genome, does not produce a new subtype, belongs to quantitative change, no qualitative change. Mostly cause small and medium epidemics of influenza. Antigen drift: Large-scale or complete mutation of influenza virus antigens.
- Name
- Antigenic variation
- Classification
- Antigen drift and antigen drift
- Solid
- Mutation of viral antigens
- Belongs to
- Natural variation
Name: Antigen Variation
Explanation
For example, the surface antigens of influenza a virus, neuraminidase and hemagglutinin, are constantly mutating. When a large mutation occurs, new influenza virus subtypes are formed. Because the population is not immune to it, it is easy to form a worldwide pandemic This is also the main reason why humans fail to control the flu epidemic.
A natural variant common to influenza A viruses. The highest mutation rate was HA (hemagglutinin), followed by NA (neuraminidase).
classification
