Nimesulide is a non-steroidal anti-inflammatory drug that can be used for the treatment of chronic arthritis (such as osteoarthritis, etc.), pain after surgery and acute trauma, and symptoms of primary dysmenorrhea.
Basic Information
- Drug Name
- Nimesulide
- Name
- Nimesulide
- Whether prescription drugs
- prescription
- Main indications
- Chronic arthritis pain, primary dysmenorrhea
- Main medication contraindications
- Prohibited for children under 12 years
- Dosage form
- powder
- Drug type
- chemical
- Molecular formula
- C13H12N2O5S
Nimesulide indication
Second-line medication for anti-inflammatory and analgesic. It is used for the treatment of chronic arthritis (such as osteoarthritis), pain after surgery and acute trauma, and symptoms of primary dysmenorrhea. Use only if at least one other NSAID treatment has failed.
Nimesulide adverse reactions
This product is well tolerated, and occasional adverse reactions include heartburn, nausea and stomach pain, sweating, flushing of the face, excessive excitement, rash, erythema, and insomnia. Rare headaches and dizziness. There have been reports of liver damage.
Nimesulide notes
Patients with renal insufficiency should adjust the dose; it is recommended to use the smallest effective dose and the shortest course of treatment to reduce the occurrence of adverse drug reactions.
Nimesul use contraindications
Patients with active peptic ulcer, moderate to severe liver dysfunction, severe renal dysfunction (creatinine clearance rate of less than 30ml / min), children under 12 years old and other patients, as well as patients with high sensitivity to the drug in the past and pregnant women are prohibited.
Use with caution in patients and lactating women who are allergic to aspirin or other non-steroidal anti-inflammatory drugs.
Patients with bleeding disorders, gastrointestinal disorders, or patients receiving anticoagulants or antiplatelet aggregation drugs should be used with caution.
Nimesulide drug interactions
1. Decrease the bioavailability and plasma concentration of furosemide.
2. Nimesulide can replace salicylic acid, furosemide, and tolbutamide in combination with plasma proteins, increasing its free concentration and enhancing pharmacological effects.
Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.
