What Is the Relationship Between Renin and Aldosterone?
Aldosterone is a steroid hormone (mineral corticosteroid family) that enhances the kidney's reabsorption of ions and water molecules. It mainly acts on the kidneys to reabsorb sodium ions and water molecules.
Aldosterone, C21H28O5. 11, 21-dihydroxy-3.20-dioxo-4-pregnene-18-aldehyde (11 18) lactaldehyde (I). Yes
Hyperaldosteronism
Primary aldosteronism (orthoaldosteronism) is caused by an increase in aldosterone secretion due to a tumor or hyperplasia of the adrenal cortex. Protoaldehyde is a secondary hypertension that accounts for about 0.4 to 2% of hypertension. The peak age of onset is 30-50 years, and women are more common than men. The most common cause of this disease is aldosterone tumors, which account for about 60% to 80% of the original aldosis. Most are single adenomas, which are more common on the left.
Aldosterone spironolactone
Its receptor antagonist is spironolactone, also known as spironolactone, which competes with aldosterone to bind to the corresponding receptors in the human body. It is a potassium-sparing diuretic and the hypotensive effect of spironolactone also originates from this.